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Results for "

Taccalonolide A

" in MedChemExpress (MCE) Product Catalog:

5

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4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2416
    Taccalonolide A

    		Microtubule/Tubulin Apoptosis Cancer
    Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities . Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis . Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells .
    <em>Taccalonolide</em> <em>A</em>
  • HY-N4208
    Taccalonolide AJ

    		Microtubule/Tubulin Cancer
    Taccalonolide AJ is a semi-synthesis compound with cellular microtubule stabilizing activity. Taccalonolide AJ exhibits high potency antiproliferative activity against cancer cells, with an IC50 of 4.2 nM for HeLa cells .
    <em>Taccalonolide</em> AJ
  • HY-N3028
    Taccalonolide B

    		Microtubule/Tubulin Cancer
    Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea, with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM .
    <em>Taccalonolide</em> B
  • HY-N7669
    Taccalonolide C

    		Others Cancer
    Taccalonolides C is an anti-cancer agent .
    <em>Taccalonolide</em> C
  • HY-N11067
    Taccalonolide E

    		Apoptosis Cancer
    Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis.
    <em>Taccalonolide</em> E

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